Is there a correlation between the consumption of psychedelics and sexual performance? Even though there are anecdotal and qualitative reports implying a connection, no formal investigation has been performed to substantiate this claim. Mental health issues or side effects of selective serotonin reuptake inhibitors (SSRIs), which are frequently administered to treat depression, can often negatively influence sexual satisfaction and performance, which are considered essential for human welfare.
A clinical research was undertaken by Tommaso Barba, Hannes Kettner, Caterina Radu, and others in 2024, to explore the impact of consuming magic mushrooms online on sexual performance.
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A Deep Dive into Psilocybin
Research by Nichols, D. E. & Walter, H. has examined the relationship between psychedelic usage and the ‘hippy’ culture, noted for its pacifist stance and liberal sexual ethics. The study of psychedelics was halted by the 1971 United Nations Controlled Substances Act, but lately, there has been a resurgence with research indicating potential mental health treatment benefits.
Let’s start by tracing back the historical background of magic mushrooms:
| Era | Event |
| Prehistoric Times | Psychoactive mushrooms were consumed by early human ancestors as indicated by rock art dating back 6000 to 8000 years. |
| 1500 BCE | Ancient societies utilized psychoactive mushrooms in spiritual rituals. |
| 283-343 A.D | The ancient Chinese manuscript “Baopuzi” by Ge Hong included descriptions of intoxicating mushrooms, including Psilocybe. |
| 900-1130 CE | Mushrooms were represented in Khajuraho Temples of India, pointing to their potential religious importance. |
| 16th Century | Native Mesoamerican cultures such as the Aztecs, Mazatec, and Zapotec used Psilocybe mushrooms in religious ceremonies and daily life. |
| 1919 | Reko misidentified psychoactive mushrooms as “Teonanácatl.” |
| Late 1950s | Albert Hofmann isolated Psilocybin. |
| 1971 | The United Nations categorized psilocybin as a habit-forming substance with no medicinal benefits. |
| Early 2022 | The Canadian government allowed doctors to prescribe psilocybin as a crisis response treatment. |
| 2022 | Oregon authorizes psilocybin for adult use. |
Can Psilocybin Impact Sexual Function?
Psychedelics, when used in conjunction with therapy, can enable therapeutic experiences such as emotional release and psychological revelations. There have been cases where psilocybin therapy for anxiety and depression has proven more effective than SSRIs like escitalopram.
Major depressive disorder, a primary source of disability, is marked by severe mood lows and diminished pleasure. Sexual dysfunction, though not a primary symptom, often accompanies depression, influencing libido and arousal. SSRIs, a typical treatment for depression, can exacerbate sexual dysfunction, affecting treatment compliance and recovery. Sexual satisfaction plays a vital role in overall happiness, relationships, and physical health.
There’s evidence suggesting that psychedelics could positively affect sexual feelings and behaviors, fostering empathy and openness. Psychedelics have been linked with increased mindfulness, empathy, body positivity, and openness to new experiences, which might affect sexual attitudes.
Potential Impact of Psychedelics on Sexual Function
Psychedelics can affect sexual functioning. Sexual activity encompasses physical and emotional aspects. Dr. Michele Leno, a licensed psychologist with Medical News, emphasizes the significance of mental states before engaging in sexual activity.
Sexual self-consciousness is a widespread problem. While some kinds of magic mushrooms available online can relieve anxiety, others, akin to alcohol, may adversely affect sexual performance. Studies suggest that individuals who microdose magic mushrooms experience decreased inhibitions and enhanced relaxation, without sacrificing performance.
Dr. Hellerstein suggests that consumption of magic mushrooms can encourage social connections, reduce self-focused thoughts, and potentially stimulate brain plasticity and empathy. These effects might explain some of the observed outcomes.
Despite the high hopes associated with psychedelic treatment, executing blind studies remains a hurdle. Clinical psychologist Dr. Carla Manly proposes that consuming whole mushrooms may appeal to those seeking altered states of consciousness, potentially enriching sexual experiences.
While some people favor natural experiences, others express feeling less restricted and more expansive when using magic mushrooms procured online. From a neurobiological standpoint, psilocybin,
This psychedelic compound, frequently used, shows parallels with certain brain imaging studies conducted under anesthesia.
What Does Recent Research Suggest?
In 2024, a study was carried out by Tommaso Barba, Hannes Kettner, Caterina Radu, among others, to explore the effect of psychedelic substances on sexual functionality and satisfaction. The research was split into two distinct studies:
- The first study examined the use of psychedelics for recreational and wellness reasons (an observational survey).
- The second study looked at the effects on patients who are experiencing depression (a controlled clinical trial).
Insights from the Recreational Use Study
- After using psychedelics, participants reported improved communication with partners, increased sexual pleasure, and greater satisfaction with their partners and their self-image.
- They also exhibited an increased openness towards sexual exploration and perceived sex as a more spiritual experience.
The effects mentioned above were still noticeable both 4 weeks and 6 months after the psychedelic experience. The only difference related to gender was observed in partner satisfaction after 6 months.
Outcomes from the Controlled Clinical Trial for Depression Patients
Depressed patients who received psilocybin therapy reported similar improvements.
- Enhanced communication with partners, increased sexual pleasure, and greater satisfaction with their partners and themselves were reported. However, patients treated with escitalopram only showed improvements in self-image satisfaction, with no other changes noticed.
- Patients who received psilocybin therapy also showed an increase in sexual interest, activity, and arousal, unlike those treated with escitalopram.
- Anxiety linked to sexual activity decreased for patients treated with psilocybin, but it increased for those treated with escitalopram.
Note: The findings indicate that these psychoactive substances could positively impact sexual functionality and well-being. The differences observed between the effects of psilocybin and escitalopram may be due to their distinct methods of action in treating depression. SSRIs like escitalopram may cause sexual dysfunction due to their specific therapeutic mechanism.
to their influence on serotonin levels, while microdosing with psilocybin directly impacts serotonin receptors. More research is needed to fully comprehend the immediate effects of these mushroom species on sexual function.Online Availability of Psilocybin Mushrooms
The use of top-quality magic mushrooms, particularly traditional varieties like psychedelic mushrooms, mushroom edibles or mushroom tea, microdosing capsules, LSD, and DMT, is thought to enhance sexual pleasure. Here are some top-notch magic mushroom products you may want to explore:
| Product Name | Zenly LSD Gel Tabs | Zenly LSD Gummies | Albino Penis Envy |
| Type | Microdosing Capsules | Edibles | Magic Mushroom |
| Active Ingredient | Lysergic Acid Diethylamide (LSD-25) | Lysergic Acid Diethylamide (LSD-25) | Psilocybe cubensis (magic mushroom) |
| Dosage | Total 600ug/6 Tabs (100ug/Tab) | Total 200ug/2 Gummies (100ug/Gummy) | 1 to 1.5 grams |
| Instructions | Consume one full tab and wait at least 2 hours before taking another for the complete experience. | Eat one whole gummy and wait for at least 2 hours before consuming another for the full effect. | Ingest 1 to 1.5 grams of dried magic mushrooms in a relaxed environment. Keep yourself well hydrated throughout the experience. |
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Frequently Asked Questions
How Long Do Psilocybin’s Effects Last?
The psychedelic impact of psilocybin generally endures from 4 to 8 hours, though this duration may fluctuate based on factors like dosage and mushroom species.
An investigation with 18 subjects confirmed that the psychedelic experience typically wraps up around the seventh hour. Visible physiological effects start to appear after two hours, reaching their peak after three hours.However, additional research is needed to comprehend the impact of elements like stress and metabolic rate. Several studies, such as this one, customize the dosage to match the participant’s body weight, assuming a uniform distribution of psilocybin in the body.
How Does Psilocin Impact the Brain?
Psilocin enters the brain roughly 30 minutes after ingestion, primarily affecting the serotoninergic system and mimicking the role of serotonin. As a neurotransmitter, serotonin plays various roles in the brain, including assisting in learning, memory, and mood regulation.
The cerebral cortex contains most of the serotonin receptors, which psilocin binds to, including 5-HT2B, 5-HT2C, and 5-HT1A. These receptors interact with serotonin. Psilocybin’s effects extend beyond serotonin receptors and also impact brain connectivity, as demonstrated in functional MRI scans.
Functional MRI scans show a decrease in blood flow and connection between brain areas like the medial prefrontal cortex and the posterior cingulate cortex. This reduced activity in key regions is thought to enable a more unrestricted cognitive state. Additionally, psychedelics induce an entropic brain state, characterized by increased disorder but improved overall connectivity.
How Does the Liver Metabolize Psilocybin?
- After ingesting psilocybin, it is absorbed into your bloodstream via your stomach and intestines.
- Thorough mastication of magic mushrooms facilitates absorption.
- Once it enters your bloodstream, it travels to your liver through the hepatic portal vein, where most of the metabolic process occurs.
- Magic mushrooms and truffles are rich in psilocin, their active ingredient. When consumed naturally, they already transforms into psilocin within our bodies.
Another crucial liver function is the ‘first pass effect,’ where approximately 50% of psilocybin is depleted during absorption before reaching the bloodstream. This phenomenon is also common with alcohol and cannabis, with individual variations possibly due to factors such as stress and activity levels. Some studies suggest that only about 20% of psilocybin is likely to convert into psilocin.
How Can Sexual Function Be Enhanced Without Resorting to Drugs or Psychedelics?
There are several ways to boost sexual function without the use of drugs or psychedelics. Here are a few suggestions:
- Address any sexual anxieties through therapy or self-reflection.
- If medications are negatively affecting your sexual desire, consider discussing alternatives with your prescribing doctor.
- Employ role-play with your partner to gradually become comfortable with sexual activities.
- Explore your sexual attitudes through journaling or psychotherapeutic techniques.
- Enhance sexual function and intimacy through natural supplements, personal growth, and couples counseling.
About the Authors:
- Barba, T., Kettner, H., Radu, C., et al. “Psychedelics and sexual functioning: a mixed-methods study,”. Sci Rep 14, 2181 (2024). https://doi.org/10.1038/s41598-023-49817-4
- Nichols, D. E. & Walter, H. “The role of psychedelics in psychiatry’s history,” Pharmacopsychiatry 54(04), 151–166 (2021).
- Dr. Michele Leno & Dr. Hellerstein: Vogel, K. “Psychedelics could enhance sexual function for up to 6 months,” Medical News Today. (2024). https://www.medicalnewstoday.com/articles/psychedelics-psilocybin-lsd-help-improve-sexual-function
Further Author Information
Tommaso Barba, Hannes Kettner, Caterina Radu, Joseph M. Peill, Leor Roseman, David J. Nutt, David Erritzoe, Robin Carhart-Harris & Bruna Giribaldi
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